Alzheimer’s Precursors Founds at Earlier Age





Scientists studying Alzheimer’s disease are increasingly finding clues that the brain begins to deteriorate years before a person shows symptoms of dementia.




Now, research on a large extended family of 5,000 people in Colombia with a genetically driven form of Alzheimer’s has found evidence that the precursors of the disease begin even earlier than previously thought, and that this early brain deterioration occurs in more ways than has been documented before.


The studies, published this month in the journal Lancet Neurology, found that the brains of people destined to develop Alzheimer’s clearly show changes at least 20 years before they have any cognitive impairment. In the Colombian family, researchers saw these changes in people ages 18 to 26; on average, members of this family develop symptoms of mild cognitive impairment at 45 and of dementia at 53.


These brain changes occur earlier than the first signs of plaques made from a protein called beta amyloid or a-beta, a hallmark of Alzheimer’s. Researchers detected higher-than-normal levels of amyloid in the spinal fluid of these young adults. They found suggestions that memory-encoding parts of the brain were already working harder than in normal brains. And they identified indications that brain areas known to be affected by Alzheimer’s may be smaller than in those who do not have the Alzheimer’s gene.


“This is one of the most important pieces of direct evidence that individual persons have the disease and all the pathology many years before,” said Dr. Kaj Blennow, a professor in clinical neurochemistry at the University of Gothenburg in Sweden, who was not involved in the research.


Dr. Nick Fox, a neurologist at University College London, who was also not part of the research, said the findings suggested that “some of the things that we thought were more downstream may not be quite so downstream; they may be happening earlier.”


That, in turn, said Dr. Fox, who wrote a commentary about the findings in Lancet Neurology, could have implications for when and how to treat people, because “there may be targets to attack, whether it’s high levels of a-beta or whatever, when people are still functioning very well.”


The Colombian family suffers from a rare form of Alzheimer’s that is caused by a genetic mutation; it strikes about a third of its members in midlife. Because the family is so large and researchers can identify who will get the disease, studying the family provides an unusual opportunity to learn about Alzheimer’s causes and pathology.


Researchers, led by Dr. Eric Reiman of the Banner Alzheimer’s Institute in Phoenix, and in Colombia by Dr. Francisco Lopera, a neurologist at the University of Antioquia, recently received a grant from the National Institutes of Health to conduct a clinical trial to test a drug on family members before they develop symptoms, to see if early brain changes can be halted or slowed.


The studies in Lancet Neurology used several tests, including spinal taps, brain imaging and functional M.R.I.


“The prevailing theory has been that development of Alzheimer’s disease begins with the progressive accumulation of amyloid in the brain,” Dr. Reiman said. “This study suggests there are changes that are occurring before amyloid deposition.”


One possibility is that brain areas are already impaired. Another possibility, experts said, is that these brain differences may go back to the young developing brain.


“It is a genetic disease, and it’s not hard to imagine that your gene results in some differences in the way your brain is formed,” said Dr. Adam Fleisher, director of brain imaging at the Banner Institute and an author of the studies.


In one of the Lancet Neurology studies, researchers examined 44 relatives between ages 18 to 26. Twenty had the mutation that causes Alzheimer’s. The cerebrospinal fluid of those with the mutation contained more amyloid than that of relatives without it. This was striking because researchers know that when people develop amyloid plaques — whether they have early-onset or late-onset Alzheimer’s — amyloid levels in their spinal fluid are lower than normal. That is believed to be because the fluid form of amyloid gets absorbed into the plaque form, Dr. Reiman said.


So, the high level of amyloid fluid in the Colombian family supports a hypothesis about a difference between the beginning phases of genetic early-onset Alzheimer’s and the more common late-onset Alzheimer’s. The difference may be that early-onset Alzheimer’s involves an overproduction of amyloid, while late onset involves a problem clearing amyloid from the brain.


In another result, when the subjects performed a task matching names with faces, those with the mutation had greater activity in the hippocampus and parahippocampus, areas involved in memory. Dr. Reiman suggested this could mean that the pre-Alzheimer’s brain has to expend more effort to encode memories than a normal brain.


Researchers also found that the mutation carriers had less gray matter in areas that tend to shrink when people develop dementia. Dr. Fox emphasized that seeing less gray matter so early was so novel that it should be treated cautiously unless other studies find a similar result.


In the second study, brain imaging was used to look for amyloid plaques in 50 people ages 20 to 56: 11 with dementia, 19 mutation carriers without symptoms and 20 normal family members. Plaques occurred at an average age of 28, more than 15 years before cognitive impairment would be expected and two decades before dementia.


The study also found that amyloid plaques increased steadily until about age 37, after which the brain did not seem to gain many more plaques. Dr. Blennow said that while researchers know that amyloid plaques plateau when people already have dementia, they did not know that the plateau appears to occur years before.


The researchers are currently analyzing data from family members ages 7 to 17 to see if some of the brain changes occur at an even younger age.


“Some people think that that may be scary, that you can see it so many years before,” Dr. Reiman said. “But it seems to me that that provides potential opportunities for the development of future therapies.”


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Group mobilizing young people to push for national debt plan









WASHINGTON — Kicking the can down the road on the skyrocketing national debt could hurt young people more than anybody. And now they are organizing to fight back.

A new group, the Can Kicks Back, aims to give Americans 18 to 32 years old a voice in the debate over tax hikes and budget cuts that loom next year if Congress and President Obama cannot agree on a deficit-reduction plan.

"Young people are struggling in this economy, and our goal is to demonstrate how the growing national debt is impacting that problem," said Ryan Schoenike, a co-founder of the group.





Part of that effort will be sending a giant mascot character in the shape of a can to college campuses to generate support, and then to Congress to highlight the concerns of young people. The group is focusing on how the debt affects the ability of people to get a job, pay for their education and raise a family, Schoenike said.

To drive home the point, the group is highlighting the share of the national debt being shouldered by every American.

Although the U.S. national debt officially is about $16.25 trillion, the Can Kicks Back is using a much higher figure — $71 trillion — which includes unfunded liabilities such as Social Security, Medicare and government pensions.

Each person's share of that larger figure is $227,000 and rising, the group said.

The group's advisory board includes Erskine Bowles and Alan Simpson, the former co-chairs of the National Commission on Fiscal Responsibility and Reform that developed a sweeping deficit-reduction plan.

The Can Kicks Back is working with the Campaign to Fix the Debt, an organization founded by Bowles and Simpson that also includes leading corporate chief executives.

The group is trying to build off the engagement of many young people in the presidential election and wants to launch chapters on at least 500 college campuses by the end of the 2013 spring semester.

The group's goal is to pressure Congress and the White House to agree to "a bold, balanced and bipartisan 'grand bargain' on fiscal issues" by the Fourth of July. To do that, the group wants young people to commit to making a 30-second phone call each week to a member of Congress pushing for a deficit-reduction deal.

"It's a simple act, sort of 30 seconds to save your future," Schoenike said. The group wants those calls to add up to a "million millennial minutes."

"There's such a disconnect between what we see in the real world and what happens in Washington," said Nick Troiano, the group's other co-founder.

Comments last week by Obama and House Speaker John A. Boehner (R-Ohio) about their willingness to compromise on tax rates and revenues are a good sign for a possible compromise, but young people can add to the pressure to make a deal, Troiano said.

jim.puzzanghera@latimes.com





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Members of Congress demand fuller explanation of Petraeus affair









WASHINGTON— The woman whose complaints sparked an FBI investigation that led to CIA Director David H. Petraeus' resignation was identified Sunday as an unpaid social liaison to MacDill Air Force Base near Tampa, Fla., where Petraeus formerly was stationed.

Military sources identified her as Jill Kelley, who had complained about harassing emails that investigators traced to Paula Broadwell, a married Army reservist who was Petraeus' biographer, according to military sources.

U.S. officials say the FBI's investigation of Broadwell's emails led them to discover explicit messages between her and Petraeus suggesting they were carrying on an extramarital affair.





Also Sunday, members of Congress demanded a fuller explanation of how and when law enforcement agents learned that Petraeus was having the affair.

Petraeus told National Intelligence Director James R. Clapper about the situation Tuesday, election day, and Clapper urged Petraeus to resign. The White House first learned of the affair Wednesday, officials said, and President Obama accepted Petraeus' resignation Friday. Key members of Congress found out only hours before the public did.

Kelley, 37, was described as a close friend of Petraeus. Officials have said that Broadwell, 40, considered the woman she emailed a rival for the retired Army general's affections.

Broadwell, who has two children, could not be reached for comment.

Kelley and her husband, Scott, issued a statement to the Associated Press on Sunday evening: "We and our family have been friends with Gen. Petraeus and his family for over five years. We respect his and his family's privacy and want the same for us and our three children."

Petraeus, one of the most influential military minds of his generation, took the CIA job last year after retiring as a four-star general and having been the top U.S. ground commander in both the Iraq and Afghanistan wars.

Broadwell met Petraeus when he gave a 2006 speech at Harvard University, where she was studying for a master's degree. She decided to make Petraeus' leadership style a doctoral dissertation topic and, later, to write his biography.

She received special access to Petraeus when he was in charge of U.S. Central Command in Tampa from 2008 to 2010, according to a U.S. officer who served under him.

"She was always in Tampa, sometimes for weeks at a time, and it was always explained that she was writing a book about him," said the officer, speaking anonymously to discuss an ongoing investigation.

When Petraeus took command in Afghanistan, Broadwell started showing up there periodically too, according to several U.S. officers who served in Kabul. She often stayed for several weeks or more at Petraeus' headquarters in downtown Kabul, where she received a room at the special quarters reserved for visiting dignitaries.

"She stayed in the distinguished visitor residences on base, much like the other traveling gang of think-tankers," said an official who served in Kabul at the time. "She did travel with him a bit too."

When the biography, "All In: The Education of General David Petraeus," came out in January, the publisher's promotional materials said that Broadwell was "afforded extensive access by Gen. Petraeus, his mentors, his subordinates and his longtime friends," and that she "embedded with the general, his headquarters staff and his soldiers on the front lines of fighting."

Petraeus' resignation sent shock waves through Congress that continued on the Sunday talk shows.

Senate Intelligence Committee Chairwoman Dianne Feinstein (D-Calif.) said that when Petraeus told her Friday he was quitting over an affair, it was "like a lightning bolt."

Appearing on "Fox News Sunday," Feinstein said she wanted to know why the bureau didn't notify the intelligence committees sooner. The incident "could have had an effect on national security," Feinstein said. "We should have been told."

Feinstein backed away from her earlier statement that Obama should not have accepted Petraeus' resignation. "When you realize additional complications ... I think he did the right thing," she said. "I think the president really had no choice but to accept that resignation."

Rep. Mike Rogers (R-Mich.), chairman of the House Intelligence Committee, had questions about how the matter was handled and about the former CIA director's conduct, a senior committee aide said.





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Hathaway says 'Les Mis' made her feel deprived

NEW YORK (AP) — Anne Hathaway credits her new husband Adam Schulman for helping her get through the grueling filming of the screen adaptation of "Les Miserables."

In "Les Mis," the 30-year-old actress plays Fantine, a struggling, sickly mother forced into prostitution in 1800s Paris.

Hathaway lost 25 pounds and cut her hair for the role. She tells the December issue of Vogue, the part left her in a "state of deprivation, physical and emotional." She felt easily overwhelmed and says Shulman was understanding and supportive.

The couple wed in September in Big Sur, Calif. Hathaway wore a custom gown by Valentino whom she collaborated with on the design. Working with the designer is a memory she says she will "treasure forever."

The December issue of Vogue hits stores Nov. 20.

___

Online:

http://www.vogue.com/

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Well: Quitting Smoking for Good

Few smokers would claim that it’s easy to quit. The addiction to nicotine is strong and repeatedly reinforced by circumstances that prompt smokers to light up.

Yet the millions who have successfully quit are proof that a smoke-free life is achievable, even by those who have been regular, even heavy, smokers for decades.

Today, 19 percent of American adults smoke, down from more than 42 percent half a century ago, when Luther Terry, the United States surgeon general, formed a committee to produce the first official report on the health effects of smoking. Ever-increasing restrictions on where people can smoke have helped to swell the ranks of former smokers.

Now, however, as we approach the American Cancer Society’s 37th Great American Smokeout on Thursday, the decline in adult smoking has stalled despite the economic downturn and the soaring price of cigarettes.

Currently, 45 million Americans are regular smokers who, if they remain smokers, can on average expect to live 10 fewer years. Half will die of a tobacco-related disease, and many others will suffer for years with smoking-caused illness. Smoking adds $96 billion to the annual cost of medical care in this country, Dr. Nancy A. Rigotti wrote in The Journal of the American Medical Association last month. Even as some adult smokers quit, their ranks are being swelled by the 800,000 teenagers who become regular smokers each year and by young adults who, through advertising and giveaways, are now the prime targets of the tobacco industry.

People ages 18 to 25 now have the nation’s highest smoking rate: 40 percent. I had to hold my breath the other day as dozens of 20-somethings streamed out of art gallery openings and lighted up. Do they not know how easy it is to get hooked on nicotine and how challenging it can be to escape this addiction?

Challenging, yes, but by no means impossible. on the Web you can download a “Guide to Quitting Smoking,” with detailed descriptions of all the tools and tips to help you become an ex-smoker once and for all.

Or consult the new book by Dr. Richard Brunswick, a retired family physician in Northampton, Mass., who says he’s helped hundreds of people escape the clutches of nicotine and smoking. (The printable parts of the book’s provocative title are “Can’t Quit? You Can Stop Smoking.”)

“There is no magic pill or formula for beating back nicotine addiction,” Dr. Brunswick said. “However, with a better understanding of why you smoke and the different tools you can use to control the urge to light up, you can stop being a slave to your cigarettes.”

Addiction and Withdrawal

Nicotine beats a direct path to the brain, where it provides both relaxation and a small energy boost. But few smokers realize that the stress and lethargy they are trying to relieve are a result of nicotine withdrawal, not some underlying distress. Break the addiction, and the ill feelings are likely to dissipate.

Physical withdrawal from nicotine is short-lived. Four days without it and the worst is over, with remaining symptoms gone within a month, Dr. Brunswick said. But emotional and circumstantial tugs to smoke can last much longer.

Depending on when and why you smoke, cues can include needing a break from work, having to focus on a challenging task, drinking coffee or alcohol, being with other people who smoke or in places you associate with smoking, finishing a meal or sexual activity, and feeling depressed or upset.

To break such links, you must first identify them and then replace them with other activities, like taking a walk, chewing sugar-free gum or taking deep breaths. These can help you control cravings until the urge passes.

If you’ve failed at quitting before, try to identify what went wrong and do things differently this time, Dr. Brunswick suggests. Most smokers need several attempts before they can become permanent ex-smokers.

Perhaps most important is to be sure you are serious about quitting; if not, wait until you are. Motivation is half the battle. Also, should you slip and have a cigarette after days or weeks of not smoking, don’t assume you’ve failed and give up. Just go right back to not smoking.

Aids for Quitting

Many if not most smokers need two kinds of assistance to become lasting ex-smokers: psychological support and medicinal aids. Only about 4 percent to 7 percent of people are able to quit smoking on any given attempt without help, the cancer society says.

All 50 states and the District of Columbia have free telephone-based support programs that connect would-be quitters to trained counselors. Together, you can plan a stop-smoking method that suits your smoking pattern and helps you avoid common pitfalls.

Online support groups and Nicotine Anonymous can help as well. To find a group, ask a local hospital or call the cancer society at (800) 227-2345. Consider telling relatives and friends about your intention to quit, and plan to spend time in smoke-free settings.

More than a dozen treatments can help you break the physical addiction to tobacco. Most popular is nicotine replacement therapy, sold both with and without a prescription. The Food and Drug Administration has approved five types: nicotine patches of varying strengths, gums, sprays, inhalers and lozenges that can curb withdrawal symptoms and help you gradually reduce your dependence on nicotine.

Two prescription drugs are also effective: an extended-release form of the antidepressant bupropion (Zyban or Wellbutrin), which reduces nicotine cravings, and varenicline (Chantix), which blocks nicotine receptors in the brain, reducing both the pleasurable effects of smoking and the symptoms of nicotine withdrawal. Combining a nicotine replacement with one of these drugs is often more effective than either approach alone.

Other suggested techniques, like hypnosis and acupuncture, have helped some people quit but lack strong proof of their effectiveness. Tobacco lozenges and pouches and nicotine lollipops and lip balms lack evidence as quitting aids, and no clinical trials have been published showing that electronic cigarettes can help people quit.

The cancer society suggests picking a “quit day”; ridding your home, car and workplace of smoking paraphernalia; choosing a stop-smoking plan, and stocking up on whatever aids you may need.

On the chosen day, keep active; drink lots of water and juices; use a nicotine replacement; change your routine if possible; and avoid alcohol, situations you associate with smoking and people who are smoking.

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Flights for Thanksgiving may be best holiday-season deal









If your grim financial situation means you have to choose between flying for either Thanksgiving or the December holidays, you may get a better deal flying for Turkey Day.

The national average price for a round-trip domestic flight for Thanksgiving is $420, about the same as a year ago, according to airline ticket data analyzed by the travel booking website Priceline.com. But the national average airfare for the span that includes Christmas and New Year's Eve is up 3%, to $444.

If you had booked Thanksgiving reservations in early October, you would have paid an average airfare of $393, while the average December holiday airfare, if booked at that time, was $430, according to Priceline.





But if you waited to book your Thanksgiving flight, you are not alone.

As of Oct. 26, 78% of Americans who say they plan to travel for Thanksgiving had yet to make reservations, according to the travel website Hotwire.

Travel experts say such procrastinators may regret waiting so long.

On the busiest travel days around Thanksgiving, the average flight will be 90% full, according to Airlines for America, the trade group for the nation's largest airlines.

In contrast, the average flight throughout 2011 was 82% full. Empty airline seats are increasingly hard to find as airlines have merged, cut less-profitable routes and consolidated flights on popular routes.

"Flight reductions have reduced the number of available seats and that, coupled with holiday travel demand, is enabling fares to creep upward," said Brian Ek, a travel expert for Priceline. "The good news is that Thanksgiving airfares are back to running about flat with last year so, if you can only travel for one end-of-year holiday, that's probably the one to pick."

U.S. satisfaction falls for airlines, rises for car rental firms

American travelers are increasingly dissatisfied with the nation's airlines, but they seem pretty happy with the country's car rental companies.

For the first nine months of this year, the U.S. Bureau of Transportation Statistics received 12,145 consumer complaints about airline services, up 33.5% compared with the first nine months of 2011.

Based on complaints filed to the bureau in September alone, the biggest sources of aggravation for fliers were flight delays, cancellations, problems with baggage, ticketing and reservations and, of course, customer service.

United Airlines had the most complaints in September with 211, followed by American Airlines with 162.

Meanwhile, customer satisfaction with rental car companies has increased for the third consecutive year, according to a study released last week by J.D. Power & Associates. In fact, the satisfaction level — reaching 769 on a 1,000-point scale — is the highest in seven years.

The greatest improvement in the satisfaction rating came from the shuttle van or bus service that car rental companies use to transport customers and the daily rates and fees, according to the study.

Another big factor in raising customer satisfaction: a warm smile. The study found that car rental customers give an average rating of 795 when they are greeted at the counter with a smile, while customers who don't get a smile give an average rating of 647.

Ryanair CEO opposes seat belt use

Seat belts on airplanes are useless.

That was the latest rant by Michael O'Leary, the chief executive for Ryanair, the ultra low-cost airline based in Ireland.

O'Leary, who opposes seat belts because he is pushing for standing-room sections of his planes, called aviation authorities who disagree with him "plonkers."

"Seat belts don't matter," O'Leary told the Telegraph. "If there ever was a crash on an aircraft, God forbid, a seat belt won't save you."

hugo.martin@latimes.com





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Advice to California's GOP: Leave — or better yet, change








Memo to the California GOP:

Rough couple of weeks, huh?

First you found out that the number of registered Republicans in California has dipped below 30%, which means we are fast approaching the day when the entire state membership can fit into two golf carts.






To make matters worse, of the 1 million people who used a new online voter registration system this election cycle, only 20% registered as Republicans. And 60% of those who registered were under 35, which means your future's not looking great.

Then the dominoes really started to fall.

Gov. Brown's Proposition 30, the first general, statewide tax hike in two decades, passed so easily that the ghost of Howard Jarvis threw himself in front of a truck.

Proposition 32, an all-out attempt to defang public employee unions, got pummeled despite an infusion of last-minute anti-labor cash from Arizona.

What could be worse? I'll tell you what. In the state Legislature, Democrats won supermajorities in both houses. Do you know what that means? It's like handing your teenager a credit card, a checkbook and the car keys so he can drive to an all-night orgy.

Meanwhile, on the national front, two states said yes to recreational marijuana and three states said yes to same-sex marriage. And Mitt Romney proved that when your only loyal supporters are aging white men who still drive Buicks and watch "Matlock" reruns — in a country with an ever more diverse population — you're cooked.

It was a wipeout, a blitz, a disaster.

So now what?

Glad you asked, because as it happens, I've got some advice for the leaders and members of the California's shrinking Grand Old Party.

Your first option is to cut and run. Frankly, I regularly hear from Republicans who so despise California and everything it stands for, I'm surprised they keep subjecting themselves to so much misery. Wouldn't it be better to sell everything, pack up the station wagon and move to Georgia or Kentucky? They think, act and vote red in those states, and they probably hate California at least as much as you do.

But here's another option. You could sit tight here in the Golden State, wait for the Democrats to screw things up in Sacramento even more than they already have, and then raise your hand when the situation cries out for the voice of fiscal prudence.

The first thing you're going to have to do, though, is remake the GOP. And by that I mean that you have to get rid of the Neanderthals who dominate the party. Then you need to start grooming and promoting some common-sense fiscal moderates, provided you can locate any.

What do I mean by that?

If someone believes Barack Obama is a socialist, Communist, Marxist, Muslim, radical, black liberation theologian, non-citizen, illegitimate president or Manchurian Candidate, forget about him. He may have a shot at a career in talk radio, but he's not going to make it in California politics.

And you're not going to breathe new life into the GOP with someone who believes the answer to the state's problems is to deport a couple million Latinos, unless they're working in the garden at extremely low rates.

You should also nix anyone who believes that gay people have chosen a "lifestyle" in the way they might choose toothpaste or a pair of shoes, and can be "converted" with enough hard work and Bible study.

I know, I know. We're really thinning the field here. And I'm not even done.






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War photography exhibit debuts in Houston museum

HOUSTON (AP) — It was a moment Nina Berman did not expect to capture when she entered an Illinois wedding studio in 2006. She knew Tyler Ziegel had been horribly injured, his face mutilated beyond recognition by a suicide bombing in the Iraq War. She knew he was marrying his pretty high school sweetheart, perfect in a white, voluminous dress.

It was their expressions that were surprising.

"People don't think this war has any impact on Americans? Well here it is," Berman says of the image of a somber bride staring blankly, unsmiling at the camera, her war-ravaged groom alongside her, his head down.

"This was even more shocking because we're used to this kind of over-the-top joy that feels a little put on, and then you see this picture where they look like survivors of something really serious," Berman added.

The photograph that won a first place prize in the World Press Photos Award contest will stand out from other battlefield images in an exhibit "WAR/PHOTOGRAPHY: Images of Armed Conflict and Its Aftermath" that debuts Sunday — Veterans Day — in the Houston Museum of Fine Arts. From there, the exhibit will travel to The Annenberg Space for Photography in Los Angeles, the Corcoran Gallery of Art in Washington and The Brooklyn Museum in Brooklyn, N.Y.

The exhibit was painstakingly built by co-curators Anne Wilkes Tucker and Will Michels after the museum purchased a print of the famous picture of the raising of the flag at Iwo Jima, taken Feb. 23, 1945, by Associated Press photographer Joe Rosenthal. The curators decided the museum didn't have enough conflict photos, Tucker said, and in 2004, the pair began traveling around the country and the world in search of pictures.

Over nearly eight years and after viewing more than 1 million pictures, Tucker and Michels created an exhibit that includes 480 objects, including photo albums, original magazines and old cameras, by 280 photographers from 26 countries.

Some are well-known — such as the Rosenthal's picture and another AP photograph, of a naked girl running from a napalm attack during the Vietnam War taken in 1972 by Huynh Cong "Nick" Ut. Others, such as the Incinerated Iraqi, of a man's burned body seen through the shattered windshield of his car, will be new to most viewers.

"The point of all the photographs is that when a conflict occurs, it lingers," Tucker said.

The pictures hang on stark gray walls, and some are in small rooms with warning signs at the entrance designed to allow visitors to decide whether they want to view images that can be brutal in their honesty.

"It's something that we did to that man. Americans did it, we did it intentionally and it's a haunting picture," Michels said of the image of the burned Iraqi that hangs inside one of the rooms.

In some images, such as Don McCullin's picture of a U.S. Marine throwing a grenade at a North Vietnamese soldier in Hue, it is clear the photographer was in danger when immortalizing the moment. Looking at his image, McCullin recalled deciding to travel to Hue instead of Khe Sahn, as he had initially planned.

"It was the best decision I ever made," he said, smiling slightly as he looked at the picture, explaining that he took a risk by standing behind the Marine.

"This hand took a bullet, shattered it. It looked like a cauliflower," he said, pointing to the still-upraised hand that threw the grenade. "So the people he was trying to kill were trying to kill him."

McCullin, who worked at that time for The Sunday Times in London, has covered conflicts all over the world, from Lebanon and Israel to Biafra. Now 77, McCullin says he wonders, still, whether the hundreds of photos he's taken have been worthwhile. At times, he said, he lost faith in what he was doing because when one war ends, another begins.

Yet he believes journalists and photographers must never stop telling about the "waste of man in war."

"After seeing so much of it, I'm tired of thinking, 'Why aren't the people who rule our lives ... getting it?' " McCullin said, adding that he'd like to drag them all into the exhibit for an hour.

Berman didn't see the conflicts unfold. Instead, she waited for the wounded to come home, seeking to tell a story about war's aftermath.

Her project on the wounded developed in 2003. The Iraq War was at its height, and there was still no database, she said, to find names of wounded warriors returning home. So she scoured local newspapers on the Internet.

In 2004 she published a book called "Purple Hearts" that includes photographs taken over nine months of 20 different people. All were photographed at home, not in hospitals where, she said, "there's this expectation that this will all work out fine."

The curators, meanwhile, chose to tell the story objectively — refusing through the images they chose or the exhibit they prepared to take a pro- or anti-war stance, a decision that has invited criticism and sparked debate.

And maybe, that is the point.

___

Plushnick-Masti can be followed on Twitter at https://twitter.com/RamitMastiAP

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Mind Faded, Darrell Royal’s Wisdom and Humor Intact Till End





Three days before his death last week at 88, Darrell Royal told his wife, Edith: “We need to go back to Hollis” — in Oklahoma. “Uncle Otis died.”




“Oh, Darrell,” she said, “Uncle Otis didn’t die.”


Royal, a former University of Texas football coach, chuckled and said, “Well, Uncle Otis will be glad to hear that.”


The Royal humor never faded, even as he sank deeper into Alzheimer’s disease. The last three years, I came to understand this as well as anyone. We had known each other for more than 40 years. In the 1970s, Royal was a virile, driven, demanding man with a chip on his shoulder bigger than Bevo, the Longhorns mascot. He rarely raised his voice to players. “But we were scared to death of him,” the former quarterback Bill Bradley said.


Royal won 3 national championships and 167 games before retiring at 52. He was a giant in college football, having stood shoulder to shoulder with the Alabama coach Bear Bryant. Royal’s Longhorns defeated one of Bryant’s greatest teams, with Joe Namath at quarterback, in the 1965 Orange Bowl. Royal went 3-0-1 in games against Bryant.


Royal and I were reunited in the spring of 2010. I barely recognized him. The swagger was gone. His mind had faded. Often he stared aimlessly across the room. I scheduled an interview with him for my book “Courage Beyond the Game: The Freddie Steinmark Story.” Still, I worried that his withering mind could no longer conjure up images of Steinmark, the undersize safety who started 21 straight winning games for the Longhorns in the late 1960s. Steinmark later developed bone cancer that robbed him of his left leg.


When I met with Royal and his wife, I quickly learned that his long-term memory was as clear as a church bell. For two hours, Royal took me back to Steinmark’s recruiting trip to Austin in 1967, through the Big Shootout against Arkansas in 1969, to the moment President Richard M. Nixon handed him the national championship trophy in the cramped locker room in Fayetteville. He recalled the day at M. D. Anderson Hospital in Houston the next week when doctors informed Steinmark that his leg would be amputated if a biopsy revealed cancer. Royal never forgot the determined expression on Steinmark’s face, nor the bravery in his heart.


The next morning, Royal paced the crowded waiting room floor and said: “This just can’t be happening to a good kid like Freddie Steinmark. This just can’t be happening.”


With the love of his coach, Steinmark rose to meet the misfortune. Nineteen days after the amputation, he stood with crutches on the sideline at the Cotton Bowl for the Notre Dame game. After the Longhorns defeated the Fighting Irish, Royal tearfully presented the game ball to Steinmark.


Four decades later, while researching the Steinmark book, I became close to Royal again. As I was leaving his condominium the day of the interview, I said, “Coach, do you still remember me?” He smiled and said, “Now, Jim Dent, how could I ever forget you?” My sense of self-importance lasted about three seconds. Royal chuckled. He pointed across the room to the message board next to the front door that read, “Jim Dent appt. at 10 a.m.”


Edith and his assistant, Colleen Kieke, read parts of my book to him. One day, Royal told me, “It’s really a great book.” But I can’t be certain how much he knew of the story.


Like others, I was troubled to see Royal’s memory loss. He didn’t speak for long stretches. He smiled and posed for photographs. He seemed the happiest around his former players. He would call his longtime friend Tom Campbell, an all-Southwest Conference defensive back from the 1960s, and say, “What are you up to?” That always meant, “Let’s go drink a beer.”


As her husband’s memory wore thin, Edith did not hide him. Instead, she organized his 85th birthday party and invited all of his former players. Quarterback James Street, who engineered the famous 15-14 comeback against Arkansas in 1969, sat by Royal’s side and helped him remember faces and names. The players hugged their coach, then turned away to hide the tears.


In the spring of 2010, I was invited to the annual Mexican lunch for Royal attended by about 75 of his former players. A handful of them were designated to stand up and tell Royal what he meant to them. Royal smiled through each speech as his eyes twinkled. I was mesmerized by a story the former defensive tackle Jerrel Bolton told. He recalled that Royal had supported him after the murder of his wife some 30 year earlier.


“Coach, you told me it was like a big cut on my arm, that the scab would heal, but that the wound would always come back,” Bolton said. “It always did.”


Royal seemed to drink it all in. But everyone knew his mind would soon dim.


The last time I saw him was June 20 at the County Line, a barbecue restaurant next to Bull Creek in Austin. Because Royal hated wheelchairs and walkers, the former Longhorn Mike Campbell, Tom’s twin, and I helped him down the stairs by wrapping our arms around his waist and gripping the back of his belt. I ordered his lunch, fed him his sandwich and cleaned his face with a napkin. He looked at me and said, “Was I a college player in the 1960s?”


“No, Coach,” I said. “But you were a great player for the Oklahoma Sooners in the late 1940s. You quarterbacked Oklahoma to an 11-0 record and the Sooners’ first national championship in 1949.”


He smiled and said, “Well, I’ll be doggone.”


After lunch, Mike Campbell and I carried him up the stairs. We sat him on a bench outside as Tom Campbell fetched the car. In that moment, the lunch crowd began to spill out of the restaurant. About 20 customers recognized Royal. They took his photograph with camera phones. Royal smiled and welcomed the hugs.


“He didn’t remember a thing about it,” Tom Campbell said later. “But it did his heart a whole lot of good.”


Jim Dent is the author of “The Junction Boys” and eight other books.



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Canada looks to lure energy workers from the U.S.









EDMONTON, Canada — With a daughter to feed, no job and $200 in the bank, Detroit pipe fitter Scott Zarembski boarded a plane on a one-way ticket to this industrial capital city.

He'd heard there was work in western Canada. Turns out he'd heard right. Within days he was wearing a hard hat at a Shell oil refinery 15 miles away in Fort Saskatchewan. Within six months he had earned almost $50,000. That was 2009. And he's still there.

"If you want to work, you can work," said Zarembski, 45. "And it's just getting started."





U.S. workers, Canada wants you.

Here in the western province of Alberta, energy companies are racing to tap the region's vast deposits of oil sands. Canada is looking to double production by the end of the decade. To do so it will have to lure more workers — tens of thousands of them — to this cold and sparsely populated place. The weak U.S. recovery is giving them a big assist.

Canadian employers are swarming U.S. job fairs, advertising on radio and YouTube and using headhunters to lure out-of-work Americans north. California, with its 10.2% unemployment rate, has become a prime target. Canadian recruiters are headed to a job fair in the Coachella Valley next month to woo construction workers idled by the housing meltdown.

The Great White North might seem a tough sell with winter coming on. But the Canadians have honed their sales pitch: free universal healthcare, good pay, quality schools, retention bonuses and steady work.

"California has a lot of workers and we hope they come up," said Mike Wo, executive director of the Edmonton Economic Development Corp.

The U.S. isn't the only place Canada is looking for labor. In Alberta, which is expecting a shortage of 114,000 skilled workers by 2021, provincial officials have been courting English-speaking tradespeople from Ireland, Scotland and other European nations. Immigrants from the Philippines, India and Africa have found work in services. But some employers prefer Americans because they adapt quickly, come from a similar culture and can visit their homes more easily.

Since 2010, about 35,000 U.S. workers a year have been issued work permits, according to Canadian immigration statistics. That's up 13% from earlier in the decade. And that figure is expected to grow as provinces continue to loosen requirements for temporary foreign workers.

Rudolf Kischer, a Vancouver-based immigration attorney, said his firm can hardly keep up with the processing of work permits for employers hiring U.S. help.

"We're the busiest we've ever been," he said.

Many of those workers are heading to where the labor market is hottest: Edmonton.

One of the fastest growing cities in Canada, this capital city owes its prosperity to the oil sands. Lying a few hours to the north, the sands are a mixture of sand, clay, water and bitumen — a heavy, black, viscous petroleum — that must be mined and processed to extract the oil. Alberta's massive deposits, which rival the conventional crude oil reserves of Venezuela and Saudi Arabia, are being developed at breakneck speed to meet the growing global demand for energy.

Edmonton has become a staging ground for oil companies that include Canada's Suncor Energy Inc., Shell Canada Ltd. and Chevron Canada Ltd. The energy sector has in turn boosted industries such as manufacturing, home building and retailing.

With a population of about 812,000, Edmonton looks a lot like many American cities. There are large strip malls anchored by U.S. retailers such as Costco and Home Depot, and ubiquitous coffee shops — except here Tim Horton's doughnut shops outnumber Starbucks 3 to 1.

The biggest difference: The unemployment rate here is 4.5%, and "We're Hiring" signs are posted in almost every window.

Moving to a city where the economy is firing on all cylinders was a sharp turn from struggling Motor City, Zarembski said.

Fat paychecks allowed him to ditch his battered Pontiac Grand Am for a late-model Dodge pickup truck. He has vacationed in the Dominican Republic and taken his 14-year-old daughter to Universal Studios in Florida. He's planning to buy a house in Edmonton's western suburbs soon.

With so much work available, Zarembski said, trade workers can afford to pick and choose. Jobs near Fort McMurray, a remote town six hours north, are the best-paid; a welder can make up $37 an hour. (At present Canadian and U.S. dollars are almost equivalent in value.) But laborers must stay in barracks-style camps, which energy companies have upgraded to woo them. The best ones offer private rooms with flat-screen TVs, gyms, prime dining and wireless Internet access.





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